Machine Learning Approach for Classification of Sickle Cell Anemia in Teenagers Based on Bayesian Network
Abstract
In this study, we employed a Bayesian network approach for the classification of sickle cell anemia in teenagers based on their medical data. Sickle cell anemia is a hereditary blood disorder characterized by the presence of abnormal hemoglobin, leading to distorted red blood cells. Early detection and classification of this condition are crucial for timely intervention and improved patient outcomes. Our research focused on leveraging the algorithmic power of Bayesian network to model and analyze a diverse set of medical parameters in teenagers, including age, platelet count, mean corpuscular hemoglobin concentration (MCHC), red blood cell count, packed cell volume etc. The Bayesian network method employed for the classification of sickle cell anemia involves using a probabilistic graphical model to represent the relationships among different medical parameters. The model incorporates Bayesian principles to update and refine its predictions as new information is introduced. The method identifies key features in the dataset that contribute significantly to the classification, providing valuable insights for early detection and intervention. The Bayesian network demonstrated remarkable efficacy in accurately classifying teenagers as either positive for sickle cell anemia or negative, achieving an impressive 99% accuracy rate. This high level of accuracy indicates the robustness of the model in discerning intricate patterns within the medical data. Key features contributing to the classification are found in the dataset, shedding light on their relevance in distinguishing between positive and negative cases of sickle cell anemia, especially in teenagers. Our findings provide valuable insights into the potential diagnostic significance of sickle cell anemia classification in the teenage population. This research contributes to the growing body of knowledge in the field of medical informatics and computational biology, offering an efficient and reliable tool for healthcare practitioners in the early identification of sickle cell anemia in teenagers. The demonstrated accuracy of the Bayesian network shows its potential as an effective decision support system, aiding clinicians in making informed decisions and facilitating timely interventions for improved patient care.
Downloads
References
D. N. Mukund, G. S. Shailesh, and A. Rajanikanth, "A Brief Bibliometric Survey of Leukemia Detection by Machine Learning and Deep Learning Approaches," Library Philosophy and Practice, 2020.
Z. Huang, J. Lin, L. Xu, H. Wang, T. Bai, Y. Pang, and T. H. Meen, "Fusion High-Resolution Network for Diagnosing Chest X-ray Images," Electronics, vol. 9, 190, 2020.
Ekong, B. Ekong, and A. E. Edet, "Supervised Machine Learning Model for Effective Classification of Patients with Covid-19 Symptoms Based on Bayesian Belief Network," Researchers Journal of Science and Technology, vol. 2, pp. 27-33, 2022.
L. Alzubaidi, M. A. Fadhel, O. Al-Shamma, J. Zhang, and Y. Duan, "Deep Learning Models Classification of Red Blood Cells in Microscopy Images to Aid in Sickle Cell Anemia Diagnosis," Electronics, vol. 9, no. 427, 2020. doi:10.3390/electronics9030427.
A. Elsabagh et al., "Artificial Intelligence in Sickle Disease," Elsevier, pp. 2-9, 2023.
U. J. Devi, M. Devaki, S. Bhusal, and V. A. Konda, "Anemia Detection using Machine Learning," International Journal of Research Publication and Reviews, vol. 4, no. 4, pp. 1996-2011, 2023.
K. J. Wenger, C. E. Koldijk, E. Hattingen, L. Porto, and W. Kurre, "Characterization of MRI White Matter Signal Abnormalities in the Pediatric Population," Children, 2023.
E. Edet and G. O. Ansa, "Machine Learning Enabled System for Efficient Classification of Intrusion Severity," Global Journal of Engineering and Technology Advances, vol. 16, no. 3, pp. 41-50, 2023.
Albayrak et al., "Sickle Cell Anemia Detection," Medical Technologies National Congress (TIPTEKNO), pp. 1-4, 2018.
T. S. Chy and M. A. Rahaman, "Automatic Sickle Cell Anemia Detection Using Image Processing Technique," in Proc. 2018 IEEE International Conference on Advancement in Electrical and Electronic Engineering (ICAEEE), pp. 1-4, 2018.
L. Alzubaidi et al., "Classification of Red Blood Cells in Sickle Cell Anemia Using Deep Convolutional Neural Network," in International Conference on Intelligent Systems Design and Applications, pp. 550-559, 2018.
B. Fang, Y. Lu, Z. Zhou, Z. Li, Y. Yan, L. Yang, G. Jiao, and G. Li, "Classification of Genetically Identical Left and Right Irises Using a Convolutional Neural Network," Electronics, vol. 8, 1109, 2019.
V. Acharya and K. Prakasha, "Computer-Aided Technique to Separate the Red Blood Cells, categorize them and Diagnose Sickle Cell Anemia," Journal of Engineering Science Technology Review, vol. 12, no. 2, 2019.
Z. Huang, J. Lin, L. Xu, H. Wang, T. Bai, Y. Pang, and T. H. Meen, "Fusion High-Resolution Network for Diagnosing ChestX-ray Images," Electronics, vol. 9, 190, 2020.
S. Nurmaini, A. Darmawahyuni, M. Sakti, M. N. Rachmatullah, F. Firdaus, and B. Tutuko, "Deep Learning-Based Stacked Denoising and Autoencoder for ECG Heartbeat Classification," Electronics, vol. 9, 135, 2020.
Download PDF: 594 times
Copyright (c) 2023 Journal of Information Systems and Informatics
This work is licensed under a Creative Commons Attribution 4.0 International License.
- I certify that I have read, understand and agreed to the Journal of Information Systems and Informatics (Journal-ISI) submission guidelines, policies and submission declaration. Submission already using the provided template.
- I certify that all authors have approved the publication of this and there is no conflict of interest.
- I confirm that the manuscript is the authors' original work and the manuscript has not received prior publication and is not under consideration for publication elsewhere and has not been previously published.
- I confirm that all authors listed on the title page have contributed significantly to the work, have read the manuscript, attest to the validity and legitimacy of the data and its interpretation, and agree to its submission.
- I confirm that the paper now submitted is not copied or plagiarized version of some other published work.
- I declare that I shall not submit the paper for publication in any other Journal or Magazine till the decision is made by journal editors.
- If the paper is finally accepted by the journal for publication, I confirm that I will either publish the paper immediately or withdraw it according to withdrawal policies
- I Agree that the paper published by this journal, I transfer copyright or assign exclusive rights to the publisher (including commercial rights)